The present invention provides a therapeutic agent for bladder irritative
symptoms associated with benign prostatic hyperplasia comprising, as an
active ingredient, a tricyclic compound represented by formula (I):
##STR00001## [wherein R.sup.1 represents a hydrogen atom, substituted or
unsubstituted lower alkyl, substituted or unsubstituted lower alkoxy or
halogen; X.sup.1-X.sup.2-X.sup.3 represents
CR.sup.5.dbd.CR.sup.6--CR.sup.7.dbd.CR.sup.8,
N(O).sub.m.dbd.CR.sup.6--CR.sup.7.dbd.CR.sup.8,
CR.sup.5.dbd.CR.sup.6--N(O).sub.m.dbd.CR.sup.8,
CR.sup.5.dbd.CR.sup.6--CR.sup.7.dbd.N(O).sub.m, CR.sup.5.dbd.CR.sup.6--O,
CR.sup.5.dbd.CR.sup.6--S, O--CR.sup.7.dbd.CR.sup.8,
S--CR.sup.7.dbd.CR.sup.8 or O--CR.sup.7.dbd.N; Y represents 13
CH.sub.2S--, --CH.sub.2SO--, --CH.sub.2SO.sub.2--, --CH.sub.2O--,
--CH.dbd.CH--, --(CH.sub.2).sub.p--, --SCH.sub.2--, --SOCH.sub.2--,
--SO.sub.2CH.sub.2-- or --OCH.sub.2--; and R.sup.2 represents a hydrogen
atom, substituted or unsubstituted lower alkyl, substituted or
unsubstituted lower alkenyl, substituted or unsubstituted lower alkoxy,
amino, mono(substituted or unsubstituted lower alkyl)-substituted amino,
di(substituted or unsubstituted lower alkyl)-substituted amino,
substituted or unsubstituted aryl, substituted or unsubstituted
heteroaryl, substituted or unsubstituted aralkylamino, substituted or
unsubstituted arylamino or a substituted or unsubstituted heteroalicyclic
group] or a pharmaceutically acceptable salt thereof.