A dental prosthesis for periodontal integration is disclosed. Furthermore a customized dental prosthesis for osseointegration is disclosed having a first manufactured portion shaped to substantially conform to the three-dimensional surface of a root of a tooth to be replaced and a second manufactured portion shaped to substantially conform to the three-dimensional surface of a crown of a tooth to be replaced. Furthermore a customized manufactured splint is disclosed to position and fixate a tooth-shaped prosthesis. Furthermore a CAD/CAM based method of and a system for manufacturing a customized dental prosthesis replacing an extracted tooth is disclosed, where the extracted tooth is scanned regarding its three-dimensional shape and substantially copied using (a) an imaging system in-vitro like a 3D scanner or in-vivo like a cone beam CT system, (b) CNC machinery and (c) biocompatible material that is suitable to be integrated into the extraction socket and at least partially adopted by the existing tissue forming the socket.