A multi-biometric finger sensor may sense different biometric characteristics that have different matching selectivities and that have at least a known spatial relationship. The sensor may include an integrated circuit substrate for receiving a user's finger adjacent thereto, and a first set of biometric sensing pixels on the substrate for sensing a first finger biometric characteristic to generate first finger biometric characteristic data having a first matching selectivity. The sensor may also include a second set of biometric sensing pixels on the integrated circuit substrate for sensing a second finger biometric characteristic different than the first finger biometric characteristic to generate second finger biometric characteristic data with a known spatial relationship to the first fingerprint characteristic data. The second finger biometric characteristic data may have a second matching selectivity less than the first matching selectivity.