An endotracheal tube for insertion into a patient's trachea includes a drug delivery feature and is formed of an elongated body having a proximal end for connection to a ventilator device and an opposing distal end with a bore formed therein and terminating in at least one ventilation opening. The tube also has at least one drug delivery conduit formed in the elongated body and terminating at one end with a proximal opening and at an opposite end with a distal opening. The proximal opening is adapted to be fluidly connected to a drug delivery device adapter, wherein the at least one drug delivery conduit is separated from the bore along its entire length thereof from the proximal opening to the distal opening. The distal opening is formed at the distal end of the elongated body and is located closer to the distal end than the ventilation opening.