Methods, kits and arrays of nucleic acid probes for genotyping large
numbers of human SNPs in parallel are provided. A set of more than
100,000 human SNPs, known to be biallelic in at least two populations is
provided. Allele specific perfect match probes and genotyping probe sets
are provided for each allele of each biallelic SNP in a set of human SNPs
that is useful for genetic analysis within and across populations. Probe
sets that include perfect match and mismatch probes are provided. The
probe sets are suitable for inclusion in an array. The invention provides
the SNP and surrounding sequence and provides the sequences in such a way
as to make them available for a variety of analyses including genotyping.
As such, the invention relates to diverse fields impacted by the nature
of genetics, including biology, medicine, and medical diagnostics.