Vacuum adherent dressings and methods and systems for using the vacuum adherent dressing are disclosed. The vacuum adherent dressing is for wound therapy of a wound having wound edges. The vacuum adherent dressing includes a flexible membrane having a top surface, a bottom surface, and a periphery. The membrane is configured to extend over the wound with the periphery of the membrane being distal from the wound edges. A fluid connector is provided on the membrane configured for attachment of a vacuum suction. Sealing jelly is disposed on the bottom surface of the membrane. The sealing jelly is configured to provide a seal between the membrane and a skin surface surrounding the wound up to and including the wound edges. One or more adhesive elements can be placed at one or more locations around the periphery of the membrane for positioning the membrane over the wound.