System and method for high-speed and high-precision digital to analog conversion. A preferred embodiment comprises a dual-resistor ladder digital-to-analog converter with a coarse resistor ladder and a fine resistor ladder, wherein resistors in the fine resistor ladder are implemented using transistors. When the effective resistances of switches used in a switching circuit are properly matched with the resistance of the resistors, the differential non-linearity and the integral non-linearity of the digital-to-analog converter can be minimized. The use of transistors to implement switches and resistors can help to eliminate mismatches arising from different fabrication steps and materials, further improving the performance of the digital-to-analog converter.