A device useful for oral drug delivery device consisting of: (a) a
capsule, tablet or pill designed to disperse in the gastrointestinal
system; (b) an RFID tag positioned in the capsule, tablet or pill, the
RFID tag comprising an antenna; (c) an object selected from the group
consisting of a magnet, a ferromagnetic object, a ferrite object and an
electromagnetic shielding object positioned within, over or adjacent the
antenna of the RFID tag to alter the antenna characteristics of the RFID
tag so that if the RFID tag is interrogated before the capsule, tablet or
pill disperses in the gastrointestinal system, the response of the RFID
tag is sufficiently altered or attenuated to determine that the capsule,
tablet or pill has not dispersed in the gastrointestinal system and so
that if the RFID tag is interrogated after the capsule, tablet or pill
has dispersed in the gastrointestinal system, the object separates from
the RFID tag so that the response of the RFID tag is sufficiently
detectable to determine that the capsule, tablet or pill has dispersed in
the gastrointestinal system. Alternatively, a switch can be used to
signal ingestion of the device, and change the response of the device.