A method of safely and specifically treating the combined metabolic
disturbances of insulin resistance and visceral adiposity in male subject
with visceral adiposity, metabolic syndrome (also known as the `insulin
resistance syndrome`, and `syndrome X`), type II diabetes, or insulin
resistance by administering a 5-alpha reductase inhibiting compound of
structural formula I, II, III, or IV is disclosed. The method is also
concerned with the use of the 5alpha reductase inhibiting compound
together with antidiabetic agents, lipid lowering agents,
antihypertensive agents, antiobesity agents, testosterone, testosterone
precursors, testosterone prodrugs, testosterone analogs, and other
androgen receptor agonists for treating visceral adiposity, metabolic
syndrome, type II diabetes and insulin resistance in men.