A system federates heterogeneous monitoring systems to provide end-to-end monitoring information for conveyances with item-layer visibility. A first node of the federated system comprises a first monitoring system and a first port and a second node comprises a second monitoring system and a second port. In parallel with a conveyance being transported between the first node and the second node, the first monitoring system sends an agent to the second monitoring system. The agent comprises logic and/or data necessary to implement processes on the second monitoring agent while the conveyance is at the second port. When the conveyance arrives at the second port, the second monitoring system executes the agent to determine conditions of the conveyance and/or its contents.