A method for producing a non-human mammalian model for neurogenic pain is
provided, which includes altering a peripheral nerve of a non-human
mammal by non-surgically placing a gel substance into the fascial tunnel
through which the peripheral nerve passes. The placement of the gel
substance leads to one or more pain behaviors thereby producing the pain
model. Also provided is a non-human mammalian model for neurogenic pain
so produced. Further provided is a method for screening a treatment or a
therapeutic agent for efficacy in treating neurogenic pain as well as a
method for screening an analgesic agent for analgesic effect in
neurogenic pain.