A system for segmenting an organ in a plurality of images is described. The system includes an imaging system configured to generate a first set of slices showing images of a subject having the organ. The system also includes a controller configured to determine a second set of slices within the first set, where the second set of slices includes the organ and a remaining set of slices within the first set of slices excludes the organ. The controller is also configured to segment the organ from the second set of slices.