Disclosed are compositions which include an isolated soft tissue from
Modiolus modiolus ("MM") and compositions which include an oil isolated
from MM or a portion thereof. Also disclosed are methods of treating
adenocarcinoma in a subject; methods of decreasing proliferation of
adenocarcinoma cells, or of inducing apoptosis of adenocarcinoma cells,
or of inducing differentiation of adenocarcinoma cells into non-cancerous
cells; methods of inhibiting the activity of 5-lipoxygenase or
12-lipoxygenase or both in cells; and methods of treating a subject
suffering from a disease or condition associated with excessive
5-lipoxygenase activity or 12-lipoxygenase activity or both. A process
for preparing an MM extract by contacting MM or a portion thereof with a
solvent under conditions effective to extract one or more materials from
the MM or portion thereof is also described.