A system for generating an animal feed formulation based on utilization of nutrients received by an animal. The system includes a simulator engine configured to generate a set of animal requirements based on characteristics of an animal and to generate animal feed formulation input based at least in part on a projected nutrient utilization for the animal and the set of animal requirements. The system further includes a formulator engine configured to receive the animal feed formulation input and generate an optimized animal feed formulation based on the animal feed formulation input.