Disclosed is a device and method which provide a surgical therapy for in
situ treatment and repair of intra-articular cartilage lesions and/or
defects. The device is an implantable laminate cartilage repair patch
which is bio-compatible and physiologically absorbable. The cartilage
repair patch has a first outer cell occlusive layer; a second outer, cell
porous layer adapted to be disposed proximate a subchondral bone wound
site; and a cartilagenic matrix disposed between the first and second
layers. The cartilagenic matrix is a sink for diffusion of autologous
stem cells and includes chemical components promoting generation of
hyaline-like cartilage in the presence of the autologous stem cells. The
method of the present invention provides the autologous compositions,
which when used in combination with the repair patch provides a
therapeutic system to regenerate replacement hyaline-like intraarticular
cartilage.