A method for producing collagen-based scaffolds with improved
characteristics, which broadens the usage of collagen in tissue
engineering and the products so produced are described. The method
comprises reconstitution of three-dimensional collagen matrices from
collagen monomer solution and crosslinking the matrix with a light source
in the presence of a photosensitizing reagent. The crosslinked products
can be in any shape and form and used in the dry or wet state, for
applications including but not limited to tissue engineering and
controlled drug delivery.