A pure pearl powder preparation method of preparing a pure pearl powder by: (a) preparing pearl and washing the prepared pearl to remove sands and other, and then infusing the washed pearl in milk/soybean milk till that the milk/soybean milk becomes rancid, (b) washing the pearl with water to remove foul smell from the pearl, and then drying the pearl, and crushing the pearl into a superfine pearl powder, and (c) mixing the superfine pearl powder thus obtained with water in a high-speed mixer to form a pearl powder suspension, and then drawing the pearl powder suspension out of the mixer through a sieve over 100 mesh, and then drying the collected pearl powder suspension at low temperature to obtain the desired pure pearl powder.