Salts and crystals of
1-cyclopropylmethyl-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine
have excellent cell adhesion inhibitory action and cell infiltration
inhibitory action, and are useful as therapeutic or prophylactic agents
for various inflammatory diseases and autoimmune diseases associated with
adhesion and infiltration of leukocytes, such as inflammatory bowel
disease (particularly ulcerative colitis or Crohn's disease), irritable
bowel syndrome, rheumatoid arthritis, psoriasis, multiple sclerosis,
asthma and atopic dermatitis.