This invention is a device (210) for sealing a hole (100) in a blood vessel (102), comprising a blood vessel engager (217) having at least one spike (214), for engaging a portion of a blood vessel (102) adjacent a hole in the blood vessel, and a body (216) coupled to the blood vessel engager (217). The device (210) has at least two configurations, a first configuration in which the device does not seal the hole, and a second configuration to which the device can be changed so that the second configuration of the device seals the hole.