A system and method for altering a selective area of tissue in a patient uses an MRI system including a coil array having a plurality of separate coil elements. Each coil element is coupled to a respective one of the RF transmitters. The method includes identifying a target tissue area in a patient and selecting a pulse sequence configured to produce a prescribed RF field at target tissue area to heat the target tissue area. An agent is administered to the patient that is configured to enhance a medical procedure and the pulse sequence is applied to the patient using the coil elements to heat the target tissue area sufficiently to assist the agent with enhancing the medical procedure. The method further includes performing a medical imaging process to at least monitor heating of the target tissue area.