Methods and apparatus are provided for implementing a cryptography accelerator for performing operations such as hash operations. The cryptography accelerator recognizes characteristics associated with input data and retrieves an instruction set for processing the input data. The instruction set is used to configure or control components such as MD5 and SHA-1 hash cores, XOR components, memory, etc. By providing a cryptography accelerator with access to multiple instruction sets, a variety of hash operations can be performed in a configurable cryptographic accelerator.