The invention relates to a compound of a general formula (I):
wherein Ar.sup.1 represents a group formed from an aromatic ring selected
from a group consisting of indole, 1H-indazole, 2H-indazole,
1H-thieno[2,3-c]pyrazole, 1H-pyrazolo[3,4-b]pyridine, benzo[b]furan,
benzimidazole, benzoxazole, 1,2-benzisoxazole and imidazo[1,2-a]pyridine;
R.sup.1 and R.sup.2 each represent a hydrogen atom, a halogen atom, a
cyano group, a C2-C6 alkenyl group, a C1-C6 alkoxy group, a halo-C1-C6
alkoxy group, a cyclo-C3-C6 alkyloxy group, a C2-C7 alkanoyl group, a
halo-C2-C7 alkanoyl group, a C2-C7 alkoxycarbonyl group, a halo-C2-C7
alkoxycarbonyl group, a cyclo-C3-C6 alkyloxycarbonyl group, an
aralkyloxycarbonyl group, a carbamoyl-C1-C6 alkoxy group, a carboxy-C2-C6
alkenyl group, or a group of -Q.sup.1-N(R.sup.a)-Q.sup.2-R.sup.b; an
optionally-substituted C1-C6 alkyl, aryl or heterocyclic group; or a
C1-C6 alkyl or C2-C6 alkenyl group having the aryl or heterocyclic group;
R.sup.3 and R.sup.4 each represent a hydrogen atom, a halogen atom, a
nitro group, a cyclo-C3-C6 alkyl group, a carbamoyl group optionally
substituted with a C1-C6 alkyl or cyclo-C3-C6 alkyl group, or a group of
--N(R.sup.e)R.sup.f; an optionally-substituted C2-C7 alkanoyl, C1-C6
alkoxy, C2-C7 alkoxycarbonyl, cyclo-C3-C6 alkyloxycarbonyl, C1-C6
alkylsulfonyl, C1-C6 alkylthio, cyclo-C3-C6 alkyloxy, cyclo-C3-C6
alkyl-C1-C6 alkoxy, cyclo-C3-C6 alkylsulfonyl, cyclo-C3-C6 alkylthio or
cyclo-C3-C6 alkyl-C1-C6 alkylthio group; or an optionally-substituted
C1-C6 alkyl group; T and U each represent a nitrogen atom or a methine
group; and V represents an oxygen atom or a sulfur atom.
The compound of the invention is useful as therapeutical agents for
various ACC-related diseases.