Catheterization device and method of using are provided for uniquely illuminating the distal end of the device in order to visualize the end-point location and orientation and to track the movement of the catheterization device within passageways in the body. Use of the present invention by tracking in real time with an imaging device sensitive to visible to near infrared light. The invention allows the insertion and tracking of substantially any catheterization type device, for substantially any procedure requiring vascular access, such as in the placement of a PICC line, for heart catheterization or angioplasty, or for urinary track catheterization, or other bodily access procedure. The invention permits a technician to determine placement, orientation and movement of the device noninvasive equipment, without subjecting the patient to the hazards associated with ionizing radiation, radio frequency energy or significant thermal energy.