The present invention relates to methods for developing and conducting a nutritional treatment program. In one embodiment, the present invention relates to methods for developing and conducting a nutritional treatment program to promote weight loss, or to treat or prevent other disease states, such as diabetes, heart disease, hypertension, etc. For example, such methods are employed to develop a diet program, and more particularly to methods for developing a program for both dieting and maintaining good nutrition both before and after losing weight. In another embodiment, the present invention relates to personalized nutritional treatment programs that are computer implemented and dynamic based on a subject's changing health condition.