Disclosed is a method for purifying teicoplanin A.sub.2 comprising: (i) a
primary pre-purification step of purifying a filtrate of fermentation
broth of a strain using a synthetic adsorbent; (ii) a secondary
pre-purification step of purifying the primary pre-purification solution
using a cation exchange resin having a high cross-linkage, a catalytic
resin or a chelate resin; (iii) a final purification step of purifying
the secondary pre-purification solution using a reversed phase resin; and
(iv) a powder-forming step. According to the present invention, it is
possible to obtain teicoplanin A.sub.2 with a higher purity through a
relatively simple process without using an excessive amount of an organic
solvent.