Wallboard, and the gypsum and paper layers that are used to prepare wallboard, can include latex compositions comprising latex particles incorporating bioactive components. Methods for preparing the latex particles, and for forming both wallboard as well as gypsum and paper layers for use in wallboard, are also disclosed. The latex compositions disclosed herein can be prepared, for example, by the emulsion polymerization of the latex component monomers in the presence of one or more of the listed bioactive components.