A method and system (100) for comprehensive knowledge-based genetic and other testing and for providing selective access to testing results (120) thereof. In particular, a method and system is provided for the personal, anonymous and confidential examination of the genetic profile of any gene or combination of genes and examining any mutations of such genes to assess the risk of developing a condition, such as a medical disease, or to identify personal characteristics and/or traits. Other data, such as chemical analysis, environmental, personal and family history of medical, behavioral, and other factors can be incorporated to generate a comprehensive knowledge-based assessment. The method and system also include features for providing secure confidential access to such assessments to third parties (160).