Disclosed herein are dietary supplement compositions and methods for
increasing or stimulating bone growth and, decreasing or preventing bone
resorption comprising a first composition comprising a combination of at
least two of: quercetin, Rehmannia sp., Rehmannia sp. root, Siberian
ginseng, Sophora japonica, licorice, and ipriflavone, wherein the
combination of the first composition increases BMP-2 gene expression,
promoter activity, or protein expression; and a second composition
comprising an extract of pomegranate in combination with at least one of
Siberian ginseng, Ginkgo biloba, green tea, Sophora japonica, Rehmannia
sp., grape seed, Dong Quai, and ipriflavone, wherein the combination of
the second composition inhibits the expression of RANK-L.