Apparatus and methods for attaching wall panels to support structures are disclosed. In one embodiment, an apparatus includes a first member and a second member. The first member is coupled to the support structure and has a first elongated coupling member. The second member has a head portion and a base portion. The head portion has at least one slot disposed therein that is adapted to receive an edge portion of the panel. The base portion includes a second elongated coupling member that is adapted to be coupled to the first elongated coupling member.