There is provided a compound of formula (I) wherein A is selected from
--O-- and --S--; X is selected from C.sub.2-C.sub.8 alkyl,
C.sub.2-C.sub.8 alkenyl, C.sub.3-C.sub.8 cycloalkyl and C.sub.4-C.sub.8
cycloalkylalkyl, each of which may be optionally substituted with up to 3
substituents each independently selected from halo, C.sub.1-C.sub.4
alkyl, C.sub.1-C.sub.4 alkoxy, C.sub.1-C.sub.4 alkyl-S(O).sub.n-- where n
is 0, 1 or 2, --CF.sub.3, --CN and --CONH.sub.2; Y is selected from
phenyl, naphthyl, dihydrobenzothienyl, benzothiazolyl, benzoisothiazolyl,
quinolyl, isoquinolyl, naphthyridyl, thienopyridyl, indanyl,
1,3-benzodioxolyl, benzothienyl, indolyl and benzofuranyl, each of which
may be optionally substituted with up to 4 or, where possible, 5
substituents each independently selected from halo, C.sub.1-C.sub.4
alkyl, C.sub.1-C.sub.4 alkoxy, C.sub.1-C.sub.4 alkyl-S(O).sub.n-- where n
is 0, 1 or 2, nitro, acetyl, --CF.sub.3, --SCF.sub.3 and cyano; and when
Y is indolyl it may be substituted or further substituted by an
N-substituent selected from C.sub.1-C.sub.4 alkyl; Z is selected from H,
OR.sub.3 or F, wherein R.sub.3 is selected from H, C.sub.1-C.sub.6 alkyl
and phenyl C.sub.1-C.sub.6 alkyl; R.sub.1 and R.sub.2 are each
independently H or C.sub.1-C.sub.4 alkyl; with the proviso that, when Z
is H, then Y may not be optionally substituted phenyl or optionally
substituted naphthyl. ##STR00001##