A particulate glass for a synthetic bone (including dental) graft includes
ZnO, SrO, and may include NaO. The glass promotes cellular metabolism,
and upon implantation in living bone tissue induces bone growth at their
surface. The ZnO and SrO respectively degrade to provide Zn.sup.2+ and
Sr.sup.2+ ions respectively. The ions released by the glass provide
anti-bacterial effects; improved bone formation in place of diseased
tissue; inhibition of bone resorption; and radiopacity. There is
excellent synergy between the SrO, ZnO, and NaO. The Sr.sup.2+ ions have
better bone formation effects than the Zn.sup.2+ ions, but an
anti-bacterial effect which is not as good. Choice of relative
proportions of ZnO and SrO combined with the choice of NaO concentration
to set the resorption rate allow optimisation. NaO there is control of
the degradation rate of the graft; a feature which is advantageous in
tailoring the grafts to specific patients and applications. Additionally
the sodium (Na) in the glass imparts water solubility, allowing glasses
to degrade to their ionic components.