Treatment of CNS disorders with (1R,4S)-trans
4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine; and
(1S,4R)-trans 4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydro-1-napthalenamine
is disclosed. A process for preparing
4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine is also
disclosed. The process includes the preparation of all four isomers of
N-[4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydronaphthalen-1-yl]formamide,
which are also useful.