A method of forming an implant to be implanted into living bone is
disclosed. The method comprises the act of roughening at least a portion
of the implant surface to produce a microscale roughened surface. The
method further comprises forming a nanoscale roughened surface on the
microscale roughened surface. The method further comprises the act of
depositing discrete nanoparticles on the nanoscale roughened surface
though a one-step process of exposing the roughened surface to a solution
including the nanoparticles. The nanoparticles comprise a material having
a property that promotes osseointegration.