A multi-layer reflective insulation system for walls, ceilings, floors, roofs and similar applications includes a sheet of multi-layer reflective insulation from a roll product. The sheet of multi-layer reflective insulation is a laminate that includes first and second pliable sheet layers with reflective major surfaces and a separation media, intermediate opposed major surfaces of the first and second pliable sheet layers, that holds the first and second pliable sheet layers in a spaced apart relationship relative to each other. The separation media creates air space between the opposed major surfaces of the first and second pliable sheet layers for the enhanced reflection of incident radiation and the emission of radiation by a reflective surface of the product.