A method for directly delivering whereby a substance is introduced into an
intradermal space within mammalian skin which involves administering the
substance through at least one small gauge hollow needle having an outlet
with an exposed height between 0 and 1 mm. The outlet is inserted into
the skin to a depth of between 0.3 mm and 2 mm such that the delivery of
the substance occurs at a depth between 0.3 mm and 2 mm.