An orally disintegrable tablet of the present invention, which comprises
(i) fine granules having an average particle diameter of 400 .mu.m or
less, which fine granules comprise a composition coated by an enteric
coating layer, said composition having 10 weight % or more of an
acid-labile physiologically active substance and (ii) an additive, has
superior disintegrability or dissolution in the oral cavity so that it
can be used for treatment or prevention of various diseases, as an orally
disintegrable tablet capable of being administered to the aged or
children and easily administered without water. Also, because the tablet
of the present invention contains fine granules having the average
particle diameter such that it will not impart roughness in mouth, it can
be administered easily without discomfort at the administration.