The invention relates to a process for preparing enantiomerically pure
alcohol of the formula 1, which comprises (i) reducing the ketone of the
formula 3to the racemic alcohol of the formula 4, (ii) enantioselectively
acylating the racemic alcohol of the formula 4 with succinic anhydride in
the presence of a lipase to give the succinic semiester of the formula 7,
(iii) separating off the succinic semiester of the formula 7 from the
unreacted enantiomer of the formula 4, (iv) reacting the enantiomerically
pure alcohol of the formula 4 with methylamine to give the
enantiomerically pure alcohol of the formula 1.