A positioning system for radiation therapy comprises a patient positioner drive unit for moving a patient positioner supporting a patient, a snout drive unit for rotating a snout including a collimator set therein, and a processing unit for controlling the snout drive unit and the patient positioner drive unit such that the positioning of the patient is performed by moving the patient positioner supporting the patient after the positioning of the collimator has been performed by rotating the snout including the collimator set therein. Exposure of the patient to X-rays irradiated for the positioning can be reduced.