A system and method for determining a coagulation time, e.g., thrombin
time, PT, aPTT, and ACT, of a blood sample deposited in a test cartridge
is disclosed. The test cartridge includes a blood receptacle that is open
to the atmosphere into which a blood sample is to be deposited, a vacuum
port that is open to atmosphere, and a spiral capillary within the test
cartridge having a capillary length and cross-section area, a first
capillary end of the spiral capillary open to the blood receptacle and a
second capillary end of the spiral capillary open to the vacuum port,
whereby the spiral capillary is closed to atmosphere. When a blood sample
is deposited in the blood receptacle, a vacuum is drawn through the
vacuum port and the blood is drawn through the spiral capillary until
coagulation occurs. A pressure change is detected, and the coagulation
time is measured.