A compound represented by the following general formula (I) or a salt
thereof, or a hydrate thereof or a solvate thereof having an inhibitory
action against plasminogen activator inhibitor-1 (PAI-1):
wherein R.sup.1 represents a C.sub.6-10 aryl group; or a substituted
C.sub.6-10 aryl group, R.sup.2 represents a C.sub.6-10 aryl group; or a
C.sub.6-10 aryl group substituted with a group or groups selected from
the group consisting of a halogen atom, nitro group, a C.sub.1-6 alkyl
group, a halogenated C.sub.1-6 alkyl group, a C.sub.1-6 alkoxy group, a
halogenated C.sub.1-6 alkoxy group, a phenyl group and carboxy group, X
represents --CH.sub.2--, --CH.sub.2CH.sub.2--, --CH.dbd.CH-- or
--N(R.sup.3)--C(.dbd.O)--, Y represents carboxy group or a bioisostere of
carboxy group, R.sup.3 represents hydrogen atom, a C.sub.1-4 alkyl group
or a C.sub.7-12 aralkyl group, m represents 0 or 1.