A method of administering a topoisomerase inhibiting agent to a mammal includes administering a pharmaceutically effective amount of a compound having the following formula or a pharmaceutically acceptable salt thereof:

 
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< APPARATUS AND METHOD FOR SYNCHRONIZING VISUAL/AUDIBLE ALARM UNITS IN AN ALARM SYSTEM

> MAINTENANCE-FREE RESPIRATOR THAT HAS CONCAVE PORTIONS ON OPPOSING SIDES OF MASK TOP SECTION
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