The present invention provides a novel piperidine derivative and a tachykinin receptor antagonist containing same, as well as a compound represented by the formula: wherein R.sup.1 is carbamoylmethyl, methylsulfonylethylcarbonyl and the like; R.sup.2 is methyl or cyclopropyl; R.sup.3 is a hydrogen atom or methyl; R.sup.4 is a chlorine atom or trifluoromethyl; R.sup.5 is a chlorine atom or trifluoromethyl; and a group represented by the formula: is a group represented by the formula: wherein R.sup.6 is a hydrogen atom, methyl, ethyl or isopropyl; R.sup.7 is a hydrogen atom, methyl or a chlorine atom; and R.sup.8 is a hydrogen atom, a fluorine atom, a chlorine atom or methyl; or 3-methylthiophen-2-yl, and a salt thereof.

 
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