Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A
(formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids
encoding the same and methods for producing the same. The homologs and
variant cellulases have the amino acid sequence of a glycosyl hydrolase
of family 7A wherein one or more amino acid residues are substituted
and/or deleted.