In order to provide a substrate for medical applications, which may be
freely elastically deformed depending on a shape of a defective portion
or hemostasis portion in a living body, is biocompatible and suitable for
tissue regeneration or cell proliferation, or hemostasis, and can be
easily manufactured. A collagen substrate of the present invention
includes a three-dimensional mesh formed of spun collagen filaments.
Preferably, the collagen substrate of the present invention includes
cotton formed of spun collagen filaments.