The present application describes compounds according to Formula I,
wherein Q, R.sup.1, R.sup.2 and X are described herein, that are useful
as Estrogen Receptor Beta (ER.beta.) modulators. Additionally, the
present application describes pharmaceutical compositions containing the
compounds according to Formula I and optionally additional therapeutic
agents. Finally, the present application describes methods utilizing the
compounds according to Formula I for modulating the function of ER.beta.
in the treatment of diseases and disorders associated with ER.beta. such
as, for example, bone disorders; cardiovascular diseases;
hypercholesterolemia; hypertriglyceridemia; vasomotor disorders;
urogenital disorders; prostatic hypertrophy; endometrial hyperplasia;
cancer and central nervous system disorders, such as, neurodegenerative
disorders. ##STR00001##