A waterless composition suitable for delivery of an active agent to a body
surface or cavity includes a vehicle having about 70% to about 99% by
weight of a hydrophilic polar solvent, said hydrophilic solvent selected
from the group consisting of (i) a mixture of two or more different
polyethylene glycols (PEGs), wherein at least one PEG is a high molecular
weight PEG having a melting point greater than 25.degree. C.; and (ii)
propylene glycol (PG); about 0% to about 10% of at least one surface
active agent; about 0% to about 5% of a polymeric agent; about 0% to
about 30% of a secondary hydrophilic solvent; and about 0% to about 5% of
a silicone oil; and about 3% to about 25% hydrophobic propellant. The
composition is otherwise substantially free of a hydrophobic solvent and
includes at least one of a surface active agent and a polymeric agent.
The vehicle and the propellant are sufficiently miscible that the
components may be homogeneously distributed with mild shaking.