The invention relates to compositions suitable for plasma substitution
comprising as a plasma expander a recombinant gelatin-like protein.
Characteristic is that the gelatin-like protein essentially is free of
hydroxyproline. This absence of hydroxyproline prevents the composition
from gelling and thus allows the use of high-molecular weight proteins in
order to establish a suitable colloid osmotic pressure. Specific
advantage of the gelatin-like proteins is that these avoid the risk of
anaphylactic shock that exists in conjunction with the use of
commercially available preparations.