This invention may provide a headphone driving circuit needless of coupling condenser even if the power supply supplies a single output voltage. The headphone driving circuit comprises (1) a first amplifier to amplify a first composite signal generated by subtracting a second channel audio signal from a first channel audio signal, then driving one end of a first voice coil of a stereo-headphone, (2) a second amplifier to amplify a second composite signal generated by subtracting the first channel audio signal from the second channel audio signal, then driving one end of a second voice coil of the stereo-headphone, (3) a third amplifier to amplify a third composite signal generated by adding the first channel audio signal and the second channel audio signal for driving the other end of the first and the second voice coil of the stereo-headphone.