Method and system are provided for calibrating a nuclear medical imaging apparatus for DC shift caused by gamma event afterglow pulses. Detector responses to weak and to high count rate radiation sources are compared with each other, and a zero correction value is incremented until the detector response is the same for the weak source and the high count rate source. The zero correction value is then stored as a static zero correction value, which multiplies a dynamic zero correction value obtained just prior to the occurrence of a gamma event, in order to remove the effects of DC shifts from the output energy signal Esum.