The invention relates to a method for the identification and/or production
of an inhibitor of hair production. Moreover, the invention relates to a
method for the inhibition of hair production. The invention also relates
to a method for the production of a pharmaceutical composition.
Furthermore, the invention relates to a pharmaceutical composition
comprising an inhibitor of hair production identified or obtained
according to one of the methods of the invention or a polynucleotide
coding for the inhibitor, optionally in a pharmaceutically acceptable
form of administration. The invention also relates to a pharmaceutical
composition which comprises a polypeptide comprising the DNA-binding
domain but not the transactivator domain of Whn, LEF-1 or Hoxc13, or a
polynucleotide coding for said polypeptide, optionally in a
pharmaceutically acceptable form of administration. Moreover, the
invention relates to the use of a polypeptide comprising the DNA-binding
domain but not the transactivator domain of Whn, LEF-1 or Hoxc13, or a
polynucleotide coding for said polypeptide, of an inhibitor identified or
obtained according to one of the methods of the invention or of a
polynucleotide coding for such an inhibitor for the production of a
pharmaceutical composition for the treatment of hair growth disorders.
Not least, the invention relates to a kit for carrying out the methods of
the invention.